Anderson provides a somewhat walkable environment, especially in its downtown area, where a traveler can find restaurants, cultural activities, and arts within walking distance. The revitalization efforts in the downtown core have improved pedestrian access with sidewalks and amenities fairly close to each other. However, the walkability significantly declines outside of downtown, where most errands will necessitate a car due to less dense amenities and sparser pedestrian infrastructure.

The public transport system in Anderson, known as CATS, consists of 7 routes but operates with limited hours, only from Monday to Friday between 8 AM and 4 PM. This schedule does not cater to travelers needing flexibility for exploring or working weekends and evenings. Moreover, while the service is affordable, the limited route coverage makes it challenging for those relying solely on public transit for daily commutes or errands.

Anderson's bikeability is on the lower side due to limited bike infrastructure, with only a few bike routes like the Artesian Rest Heartland Bikeways. The lack of widespread dedicated bike lanes and potential issues with traffic safety make cycling less practical for daily transportation needs, although it can be enjoyable for recreational rides. The hilly terrain in certain areas might also pose a challenge for casual biking as part of a commute.