Antigua Guatemala is a pedestrian's delight with its compact grid layout, making it easy to explore on foot. Central areas boast numerous amenities like cafes, shops, and historical sites within close proximity. Despite cobblestone streets and minor hills which can add a slight challenge, the convenience and charm of walking cannot be understated, allowing for a car-free existence.

Public transport in Antigua is somewhat limited, with the primary option being 'chicken buses' for travel to surrounding areas, which might not be the most comfortable. Within the city, tuk-tuks provide a taxi-like service while Uber offers an alternative. However, the absence of a comprehensive transit system means travelers shouldn't rely solely on public transport.

Biking in Antigua is feasible given the city's compact size and generally flat terrain in some areas, although the lack of dedicated bike lanes and cobblestone streets present challenges. Traffic conditions may also pose risks, but the availability of mountain biking tours in nearby areas suggests some biking opportunities exist. While biking could handle certain errands, it might not be suitable for regular commuting.