Arezzo's historic center is compact and easily navigable on foot, making it ideal for travelers who enjoy exploring by walking. The town's layout, with its mix of historical and modern elements, allows easy access to restaurants, museums, and other attractions. The proximity of key locations such as the train station to the historic center enhances its walkability, ensuring that most essential services and points of interest are just a short stroll away.

Arezzo provides a reasonably efficient public transportation system, beneficial for travelers wishing to explore both within and beyond the city. The city features about 16 bus lines that serve the historic center and the outskirts, with convenient stops near major points like Piazza Guido Monaco and the central train station. Additionally, the local train network connects Arezzo to major cities such as Florence and Rome, making it a practical choice for longer excursions. However, the frequency and reach may not cover every traveler's needs fully.

While Arezzo offers some opportunities for biking, particularly in the surrounding scenic Valdichiana area, the city's hilly terrain presents a challenge for cyclists. The 'Vittorio Fossombroni' Land Reclamation Path offers an excellent biking route outside the city, extending a 62-kilometer track to Chiusi, which appeals to more adventurous bikers. Inside the city, the limited dedicated cycling infrastructure might deter some from relying on bicycles as a primary mode of transport.