Athlone offers a moderately walkable environment, especially within its town center where most amenities are congregated by the River Shannon. This makes it relatively convenient for travelers who want to access shops, cafes, and some local attractions on foot. However, parts of the town may require some form of transport due to the layout, and the presence of major roads and the river can hinder pedestrian access, making some areas less walk-friendly.

Athlone is reasonably well-connected by public transit, with a train station offering services to major cities like Dublin and Galway, as well as several bus routes within the town and to other regions. The use of the TFI Leap Card makes payment easier on Bus Eireann services, although buses might not run as frequently, particularly on Sundays. These services provide a reliable way to travel around Athlone and to other destinations, but might require some planning ahead to maximize convenience.

Athlone is fairly bikeable, primarily due to the presence of the Old Rail Trail Greenway, which offers a safe, flat, and scenic route for both recreational and transportation purposes. This 43km path to Mullingar is a highlight for cyclists and provides an enjoyable and accessible option for exploring the region. Additionally, bike rental options like Moby Bike Hire add to the convenience. However, within the town itself, cyclists might face more challenges due to traffic or limited bike-specific infrastructure.