Greifswald is a relatively small city with a compact Altstadt (old town) that hosts a variety of amenities, making it convenient for travelers to accomplish errands by foot. The central area is rich with cafes, restaurants, shops, and historical sights, promoting a pedestrian-friendly environment, particularly around the university. However, for those needing services beyond the city center, walking alone might be less practical. The city's layout favors the pedestrian experience for daily necessities, especially for those choosing accommodation in the heart of Greifswald.

Greifswald offers a local bus network operated by Stadtwerke Greifswald, which provides reasonable coverage across the city and connects it with larger urban areas via train links. While this infrastructure facilitates accessing the city center and regional travel, the frequency and reach may not match those found in larger cities. Thus, travelers may find public transportation adequate for occasional use or for reaching destinations beyond walking range, but possibly limiting if attempting to rely on it entirely for daily commuting.

Greifswald excels as a bicycle-friendly city, with its flat terrain and dedicated bike pathways making it ideally suited for cyclists. The presence of bike-sharing programs and a vibrant cycling culture among students make biking an appealing option for travelers. Although narrow lanes and occasional car traffic present minor challenges, cycling remains a highly practical and enjoyable mode of transport for exploring the city and its surroundings. Travelers will find biking a reliable and efficient way to navigate Greifswald for both daily activities and leisure.