Grimsby offers limited walkability, primarily concentrated in the downtown core where travelers can find some shops and services. However, for a broader range of amenities such as larger grocery stores and retail areas, a car is often necessary as these are located along major roads. While certain neighborhoods are equipped with sidewalks, daily errands or larger supply shopping on foot can be quite challenging, especially without steady paths throughout the town.

Public transit options in Grimsby are quite restricted, providing limited convenience for travelers. The main public transportation service comes from NRT On Demand, offering a ride-sharing option within specific hours from Monday to Saturday. Additionally, there are hourly buses via GO Transit and limited service by Greyhound, but these do not fully cover the needs of travelers looking to navigate the town without a car. While a future GO Train station may enhance regional connectivity, current offerings require planning and reliance on arranging multiple transport modes.

Grimsby presents both opportunities and challenges for biking enthusiasts. While it offers scenic routes, such as those along the Great Lakes Waterfront Trail, dedicated bike lanes are sparse. Consequently, using a bike for daily commutes or errands can be difficult, as road traffic and limited infrastructure provide obstacles. The terrain remains accommodating along lakefront areas but can become challenging with the hilly landscapes connecting to the Niagara Escarpment.