Guatemala City offers a 'somewhat walkable' experience for travelers. Though areas like Zona 10 and Zona 4 have shops, cafes, and some services within walking distance, much of the city is sprawling and requires transport between zones. Many sidewalks are uneven or absent, adding challenges to walking. Security concerns also suggest staying vigilant to avoid pickpocketing, especially in tourist-heavy spots and markets.

Navigating Guatemala City via public transport is challenging for travelers. The Bus Rapid Transit (BRT) system, Transmetro, provides some service but can be complex for those unfamiliar with it. The widely used 'chicken buses' are often overcrowded, and security is a concern. Taxis and rideshares like Uber are safer alternatives, though Transmetro offers basic coverage, mainly operating between the outskirts and city center at limited times.

Biking in Guatemala City is possible, yet it comes with significant challenges. Some bike lanes are available but often lack maintenance and protection from the chaotic traffic. While certain neighborhoods close streets to cars for cyclists on Sundays, the city's hilly terrain and shared lanes with both pedestrians and not-so-mindful motorists mean vigilance is required for safety. Overall, regular use for commuting day-to-day may be difficult.