Hartsville, South Carolina, presents a car-dependent environment with some pockets of walkability, particularly in the downtown area. While there are a few walkable blocks catering to restaurants, shops, and parks, most areas require a vehicle for daily errands and reliable access to amenities. The layout indicates that while the downtown and North Hartsville may support some pedestrian movement, it's not consistently walk-friendly across the city.

Public transit options in Hartsville are sparse, with minimal availability likely to suit travelers seeking comprehensive transport solutions. The Pee Dee Regional Transportation Authority operates a limited bus route, primarily during weekdays with an infrequent schedule. This lack of extensive and flexible public transportation can hinder travel convenience, making it difficult for travelers relying solely on transit.

Hartsville offers a somewhat bikeable area with some infrastructure, including paths that form a loop through key parts of the city. While there's improvement in safety and connectivity, the bike paths are not extensive, and some areas present challenges due to traffic and debris. Although biking as a form of recreation is feasible, those needing to complete daily errands will find it more challenging due to the gaps in infrastructure.