High Wycombe presents challenges for walkers due to its general layout and hilly terrain, which can make navigating the area on foot somewhat impractical for daily errands. While the town center offers some walkable areas with shops and amenities, many attractions and necessities are situated further afield. For travelers or those relying solely on walking, the need for additional transport options becomes evident, especially when attempting to explore prominent attractions beyond the central area.

Travelers in High Wycombe can rely on a fair array of public transportation options. The town is served well by bus routes that connect to surrounding areas and major cities like London. Additionally, the railway station provides efficient travel to destinations such as Birmingham. An on-demand minibus service supplements these options, making it feasible to navigate the area without a car, though planning and schedule adherence are necessary.

Cycling in High Wycombe is influenced by the town's hilly landscape, which can pose difficulties for everyday commuting by bike, especially for less experienced cyclists. While there are concerted efforts to improve cycling infrastructure, current routes may still present challenges regarding safety and accessibility for all users. Cycling is thus better suited for leisure rather than being a primary mode of transport for travelers, who might prefer cycling paths that offer scenic excursions rather than practical commuting routes.