Highlands Ranch is a car-dependent suburb with a layout that is spread out, necessitating a car for most errands. While there are some areas near the Town Center that offer a few shops and restaurants within walking distance, the overall area lacks the density needed for a truly walkable lifestyle. The neighborhood referred to as "Downtown Highlands Ranch" is slightly more walkable than other parts.

Public transit in Highlands Ranch is somewhat limited, with bus lines that do exist but don't offer comprehensive coverage. The frequency of buses may not be convenient for all travelers. However, the region's proximity to RTD bus stations and light rail connections such as the County Line and Littleton/Mineral stations facilitates access to the broader Denver area. Future introduction of microtransit services might improve connectivity, but current options remain sparse.

Highlands Ranch offers some bike infrastructure, including multiple trails and paths, which makes biking possible to a certain extent. The terrain is generally accommodating, and there are recreational options for biking with around 70 miles of trails available. However, the infrastructure has noticeable gaps, and cyclists may have to navigate through areas with traffic, making it less than ideal for everyday biking.