Ierapetra's compact town center offers a traveler a highly walkable experience. Most accommodations are strategically placed within a short walking distance from the bay, restaurants, and essential services. The old town, Kato Mera, enhances the pedestrian experience with its charming narrow streets. Moreover, the town's flat terrain and vibrant coastal road make walking both easy and enjoyable.

Traveling by public transportation in Ierapetra requires a bit of planning, as it's primarily served by the KTEL bus network. While buses connect to major towns and local villages effectively, the frequency isn't high, particularly to the airport. While this system is affordable, travelers should prepare for less frequent services and occasional transfers.

Ierapetra earns its reputation as a bike-friendly location with its flat terrain and cycling routes. Though some dedicated bike lanes exist, it's the abundance of rental options and scenic routes to nearby attractions that make cycling here appealing. Biking combines seamlessly with other activities, such as beach visits, offering a practical and enjoyable way to explore both Ierapetra and its surroundings.