Itapetininga's downtown area is quite walkable, with a good mix of services and shops, allowing travelers to conduct most errands on foot. The city retains a relatively high level of safety during the day in central areas, which boosts its walkability for visitors. However, the experience might vary greatly between neighborhoods, making it important for travelers to choose accommodations close to the city center to maximize convenience and accessibility.

Itapetininga offers limited public transportation options, primarily focused on bus routes. While travelers can access other cities like São Paulo and Sorocaba via buses, the city itself lacks a comprehensive or frequent public transit system. This might mean relying more on taxis or buses for longer distances, making it less convenient for those without a personal vehicle.

Cycling infrastructure in Itapetininga is underdeveloped, with few dedicated bike lanes and no strong biking culture reported. While some trails might be available for leisure, biking is not typically a practical option for commuting. The safety concerns due to traffic conditions could also contribute to its limited viability as a primary form of transportation for travelers.